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Figure 4 Serial changes in the expression of Mac-1 activation neo-epitope (8B2 binding) on the surface of neutrophils after PCI. Antibody binding capacity (ABC) of 8B2 began to increase immediately after coronary stenting reaching a maximum at 48 h in both coronary sinus and peripheral blood. These changes were more striking in coronary sinus blood (left). The transcardiac gradient (coronary sinus blood minus peripheral blood) of 8B2 binding increased after PCI, reaching a maximum at 48 h (right). Closed circles = coronary sinus blood (CS); open circles = peripheral blood (P); squares = transcardiac gradient. *p < 0.05 vs. pre; **p < 0.01 vs. pre; ***p < 0.001 vs. pre; p < 0.01 CS vs. P. PCI = percutaneous coronary intervention.