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Figure 4 Capillary densities at different locations in the infarcted heart. CD31-positive capillary density was measured at three areas: (A) infarction, (B) peri-infarct border zone, and (C) interventricular septum and similar anatomic areas in sham-operated hearts. The number of CD31-stained capillaries was counted in a blinded fashion and expressed as the number/mm². HIF-1(+)/MI n = 10 animals, HIF-1(–)/MI n = 10 animals, HIF-1(+)/sham n = 10 animals, HIF-1(–)/sham n = 10 animals.