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Figure 1 Representative ultrasound images of atherosclerotic carotid plaques with ultrasound analysis. (A) Regular B-mode image of carotid atheroma as shown by arrowheads. Plaque-IMT_max was measured in this mode as shown by an arrow. (B) IBS-mode image. The red dotted line indicates the region of interest (ROI) in the plaque (intima-media complex), and the blue dotted line indicates the ROI in the adventitia using the manual outline definition mode. Values of cIBS and plaque-IMT_max of this plaque are –19.6 dB and 2.44 mm, respectively. CCA = common carotid artery; IBS = integrated backscatter; ICA = internal carotid artery; IMT = intima-media thickness.