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Figure 4 Electrograms recorded at eight adjacent electrodes in a synchronized culture before channel abrasion (A), immediately after channel abrasion (B) (gray squares indicate electrodes located at the channel level), and 24 h after human mesenchymal stem cell (hMSC) seeding (C). After abrasion no electrical activity is present at the level of the channel (B, E). Resynchronization of the cardiomyocyte fields and the presence of electrical activity in the channel is shown in F. Panels D and F give typical recordings of an electrode underneath a cardiomyocyte and an hMSC.