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Figure 4 Correlation of the percentage of plaque area contributing to entire vessel area (ratio of plaque area to the external elastic membrane [EEM] cross-sectional area [CSA]) determined by intravascular ultrasound (IVUS) and 64-slice computed tomography (CT). The correlation coefficient between the measurements with both methods is r = 0.61. On average, the percentage of vessel area occupied by plaque is significantly underestimated by 64-slice computed tomography (50.4% vs. 41.1%, p < 0.001).