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Figure 4 Effect of lipid lowering on plaque size according to the 100 mg/dl low-density lipoprotein cholesterol (LDL-C) goal. Changes in vessel wall area (VWA) are displayed according to the goal of 100 mg/dl (2.6 mmol/l). On treatment, LDL-C 100 mg/dl is associated with larger regression. Patients who reached the goal had a significantly higher regression in aortic lesions (left panel). A similar trend was seen for carotid lesions (right panel). The values of the last available magnetic resonance imaging examination and the baseline value were used to calculate percent changes in VWA.