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Figure 2 (A) Diabetic patients have lower levels of circulating endothelial progenitor cells (EPCs) when compared to controls. Circulating progenitor cells (CPCs) from diabetics display a similar reduction, indicating that the effect of diabetes per se is not specifically targeted to endothelial progenitors. (B) Circulating EPCs and EPC/CPC ratio were negatively correlated with blood glucose at time of blood collection. Higher glucose concentrations were associated with low absolute numbers of EPCs and low endothelial fraction of all progenitors. Mean values ± SE. CTRL = control subjects; DM = diabetes mellitus.