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Figure 4 Platelet P-selectin expressions in vivo in wild-type (P+/+) and P-selectin-deficient (P–/–) mice (A and B). Ferric chloride (FeCl3) application increased in vivo expressions of platelet P-selectin only in P+/+ mice but not in P–/– mice (C). Platelet P-selectin expressions in P–/– mice were similar to those in the negative control (fluorescein isothiocyanate [FITC] immunoglobulin G [IgG]).