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Figure 2 Shear rate determination from velocity profile. (A) The velocity profile measured at segment I at one moment during the cardiac cycle after smoothing is applied. (B) Visualization of determination of velocity gradient (dv/dr). (C) Shear rate at each pixel in the lumen. (D) Determination of shear rate at the vessel wall, with the maximum shear rate in regions of approximately 22.5° at the outer 10% of the radius. (E) Shear rate at 16 locations along the circumference; these are summarized into four quadrants per cross section.