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Figure 3 Effect of blood pressure lowering in different studies comparing calcium (Ca) channel blocker-based treatment regimens (top panel) or angiotensin-converting enzyme (ACE) inhibitor–based regimens (bottom panel) versus thiazide (Th/Thi/Thiaz.) and/or beta-blocker (BB)–based regimens on cardiovascular outcomes and all-cause mortality. CI = confidence interval; RR = risk ratio. Reproduced from the National Institute of Clinical Excellence Clinical Guideline 18 (4), with permission.