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Figure 5 Point estimates for change in risk of number of patients hospitalized for worsening heart failure with metoprolol controlled release/extended release (CR/XL) compared with placebo and 95% confidence intervals (Cox-adjusted) in relation to baseline heart rate (upper panel) and achieved heart rate at last follow-up visit (lower panel) in the five quintiles (Q) defined by baseline resting heart rate. Data also given for Q1 to Q4 merged into one group (Q1-4) and for all patients randomized. Mean heart rate and number of patients hospitalized (hosp.) in the two randomization groups are also given for each quintile. bpm = beats/min; CHF = chronic heart failure; meto = metoprolol.