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Figure 3 Point estimates for change in risk of total mortality with metoprolol controlled release/extended release (CR/XL) compared with placebo and 95% confidence intervals (Cox adjusted, see Statistical methods section for details) in relation to baseline heart rate (upper panel) and achieved heart rate at last follow-up visit (lower panel) in the five quintiles (Q) defined by baseline resting heart rate. Data also given for Q1 to Q4 merged into one group (Q1-4) and for all patients randomized. Mean heart rate and number of deaths in the two randomization groups are also given for each quintile. bpm = beats/min.