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Figure 2 A discrepancy between activation of the coagulation cascade and circulating inflammatory markers in unstable angina (UA) (open boxes) and peripheral artery disease (PAD) (shaded boxes). Thrombin-antithrombin III complexes (TAT) (A) and D-dimers (DD) (B) were significantly higher in patients with PAD than in patients with UA. Conversely, interleukin (IL)-6 (D) and C-reactive protein (CRP) levels (C) were significantly higher in patients with UA than in patients with PAD. Moreover, activation of neutrophils, indicated by the significant reduction of their myeloperoxidase content (MPXI) (E) was only present in patients with UA. Data are shown as the median values, 25% to 75% interquartiles, and range.