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Figure 5 Representative examples of in vivo wavelet analysis of radiofrequency (RF) intravascular ultrasound (IVUS) signals from a lipid-laden plaque (A) and from a fibrous plaque without a lipid core (B). The left panels show conventional IVUS images, the middle panels show the results of wavelet analysis, and the right panels show the histologic cross sections of the corresponding directional coronary atherectomy specimen with hematoxylin-eosin and Azan stains. A similar pattern of color mapping was observed from the radiofrequency signal vector of a lipid-laden plaque, as seen in the in vitro study.