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Figure 2 Overview (A) and details (left: B, C; mid: D, E; right: F) of the atherectomy specimen obtained six months following stent placement. Histology shows a mixture of myxoid (B, C) and fibrous material (F) consisting of smooth muscle cells (C, E) within variable amounts of extracellular matrix. Some fragments contained thrombus remnants (Th) (D, E) and calcifications (Ca) (F). A = elastin stain; B, D, F= hematoxylin eosin; C, E = immunocytochemistry for smooth muscle cell-specific alpha actin.