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Figure 6 Expression of tissue factor (TF) (A) and generation of prothrombin fragment (F1+2) (B) in monocytes taken from healthy subjects (2 men and 2 women, mean age 50 years) and stimulated with scalar doses of CD40 ligand (CD40L) (5 to 50 ng/ml). UM = unstimulated monocytes; SM = stimulated monocytes. *p < 0.001 for CD40L (5 ng/ml) SM vs. UM. **p < 0.0001 for CD40L (25 ng/ml) SM versus UM and CD40L (50 ng/ml) SM versus UM.