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Figure 4 Stroke Prevention with an ORal Thrombin Inhibitor in Atrial Fibrillation (SPORTIF)-III trial: event-rate comparisons for various composite end points and sensitivity analyses. Comparisons are presented first for the primary objective, then the two secondary objectives, two prespecified sensitivity analyses for the primary end point, and an exploratory, post-hoc analysis (47). ITT = intention-to-treat analysis; MI = myocardial infarction; OT = on-treatment analysis; SEE = systemic embolic event; TIA = transient ischemic attack.