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Figure 2 Impact of initiating carvedilol before perindopril therapy (beta-blocker [BB]-first group) compared with the effect of the commencement of perindopril first (angiotensin-converting enzyme inhibitor [ACEI]-first group) on left ventricular ejection fraction (EF), determined using radionuclide techniques. *p < 0.05; **p < 0.001 versus baseline data (0 months); p < 0.05 versus absolute values and change from baseline in the ACEI-first group. Muga = multiple gated equilibrium cardiac blood pool scintigraphic technique.