Click on image to view larger version.

Figure 1 Impact of initiating carvedilol before perindopril therapy (beta-blocker [BB]-first group) compared with the effect of the commencement of perindopril first (angiotensin-converting enzyme inhibitor [ACEI]-first group) on New York Heart Association functional class (NYHA FC). *p < 0.05 versus baseline data (0 months); p < 0.05 versus absolute values and change from baseline in the ACEI-first group.