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Figure 5 Change in sSR (A) and TRL (B) from baseline to peak dobutamine stress was significantly lower in ischemic versus normal segments (both p < 0.0001; dashed lines = mean, solid lines = 1 SD). Using a combination of the best cutoff values for change in sSR and TRL significantly increased the specificity compared with sSR and TRL alone (C). Open circles = control segment response; black circles = ischemic segment response. (D) Receiver operating characteristic curves demonstrated that the area under the curve was similar for sSR compared with TRL, and was higher for sSR + TRL compared with TRL alone (p = 0.01) and for sSR alone (p = 0.05). Abbreviations as in Figure 2.