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Figure 2 The myocardial tissue perfusion unit (TPU) (A and C) and pH (B and D) are shown at baseline, 30 and 60 min after coronary occlusion, 30 and 60 min of ultrasound exposure, 30 min after stopping ultrasound, and 15 min after opening the coronary artery. Panels A and B are combined data from eight dogs and four pigs. The hashed lines demonstrate the results when the animal (three dogs) was pretreated with L-NAME. C and D show the data for each species (dogs and pigs). The thin line indicates dog data, and the thick line is for pig data. *p < 0.05 for 60-min occlusion versus during ultrasound at 30 or 60 min and after opening the coronary artery.