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Figure 3 Bar graphs showing effects on serum total cholesterol (A) and collagen (2 µg/ml)-induced whole blood platelet aggregation (B). Platelet aggregation was measured by impedance aggregometry (Chronolog, Havertown, Pennsylvania) and data expressed as the maximal change in impedance in ohms (ohms_max) at 6 min after the addition of collagen. Values are mean ± SEM. *p < 0.05; **p < 0.001 vs. apoliprotein E (ApoE), analysis of variance. DPPC = 1,2-dipalmitoyl-sn-3-phosphoglycerocholine; WT = wild-type.