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Figure 2 Plasma atrial natriuretic peptide (ANP) concentrations in normal subjects, asymptomatic cardiovascular (CV) disease subjects with normal or elevated pulmonary capillary wedge pressures (PCW), and symptomatic heart failure patients (CHF) with elevated PCW pressure. (Adapted, with permission, from Burnett JC Jr., Kao PC, Hu DC, et al. Atrial natriuretic peptide elevation in congestive heart failure in the human. Science 1986;231:1145–7.)