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Figure 1 Comparisons by analysis of variance of rest and exercise ejection fraction (EF) (A) and effective arterial elastance index (EaI)/left ventricular systolic elastance index (ELVI) (B) in men (dashed lines) and women (solid lines) <40 years of age (solid triangles) (mean age, 32.4 ± 4.7 years and 31.2 ± 4.9 years, respectively) and >60 years of age (solid squares) (mean age, 68.9 ± 6.8 years and 70.4 ± 7.1 years, respectively). Ejection fraction increases with exercise in both age groups and genders (p ≤ 0.0001). In both men and women, there is a greater increase in EF at maximal exercise in younger than in older subjects (p ≤ 0.001 for men and women); EaI/ELVI decreases with exercise in both age groups and genders (p ≤ 0.0001). In both men and women, there is a greater decrease in EaI/ELVI at maximal exercise in younger than in older subjects (p ≤ 0.0001 for men and women).