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Figure 1 Functional effects of CD133+ and skeletal myoblast (SM) cell transplantation. (A) Individual values and mean percentage of change in left ventricular ejection fraction (LVEF) from baseline pretransplantation values in controls (n = 9; open triangles), CD133+-treated (n = 15; closed circles), and SM-treated (n = 8; closed triangles) hearts. (B) Representative tracings of pressure-volume occlusion loops. (C and D) Individual values and means of (C) maximal elastance (Emax) and (D) preload-recruitable stroke work (PRSW) in controls (n = 9), CD133+-grafted (n = 12), and SM-grafted (n = 7) hearts. Note the functional improvement in >25% of CD133+-grafted and SM-grafted animals.*p = 0.0015, {dagger}p = 0.008, {ddagger}p = 0.01 vs. controls.