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Figure 5 Effect of anti-glycoprotein (GP) IIb/IIIa agents on platelet thrombi formed on the collagen surface. The experiments were performed in a manner similar to that described in the legend for Figures 1 and 4. The three-dimensional structure of the platelet thrombi formed on the collagen surface after 6-min perfusion of blood on the collagen surface at 1,500 s^–1 was quantified by calculating the cross-sectional areas of the platelet thrombi using the National Institutes of Health image software at every 3 µm from the collagen surface. The results are expressed as a percentage of the largest cross-sectional area obtained at the collagen surface level. The results shown are the mean and standard error of eight replicated experiments. Similar results were obtained in the condition when blood was anticoagulated by heparin.