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Figure 2 Change in global myocardial blood flow reserve (MBFR) in response to adenosine infusion. [13N]ammonia positron emission tomography was used to explore MBF regulation in response to adenosine. p < 0.05 diabetic control subjects (DC) versus controls (C). p < 0.05 early microangiopathy (DMA+) versus C and DC. Horizontal bars = mean value.