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Figure 4 Alignment of Tcap amino acid sequences. The amino acid sequence of human Tcap was aligned with that of bovine, rat, and mouse Tcaps. The mutations found in patients with hypertrophic cardiomyopathy (HCM) and dilated cardiomyopathy (DCM) are represented along with the phosphorylation site, Ser157, indicated by an arrowhead. Dashes indicate identity to human Tcap.