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Figure 2 Acute angiographic response to mibefradil. An example of the angiographic response to a single oral dose of 50 mg mibefradil in a patient with the coronary slow flow phenomenon (CSFP). The angiographic snapshots presented were taken exactly three heart beats after contrast filled the width of the left main coronary artery. (A) Recorded before mibefradil administration and demonstrates incomplete opacification of the left anterior descending and circumflex arteries at three beats, thereby confirming the diagnosis of the CSFP. (B) Demonstrates improved vessel opacification 30 min after mibefradil administration.