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Figure 1 Western blot analysis of heart tissue for GLUT4 and GLUT1 proteins. As expected, there is an absence of the GLUT4 protein in homozygous (–/–) GLUT4-null mice. The GLUT1 protein displays a twofold increase in GLUT4-null mice (–/–) compared with wild-type mice (+/+). GLUT = glucose transporter.