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Figure 1 (a) The majority of calcified stenotic valves studied, as in this case, are occupied by calcium deposits (violet area, hematoxylin-eosin [HE]). (b) Case 12: areas with ossification and bone marrow formation were observed in a calcified aortic valve leaflet (HE). (c) Sample of normal aortic valve from control patient showing slight thickening and fibrosis of the valve leaflet (HE).