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Figure 5 Effects of peroxisome proliferators-activated receptor-alpha activator on nuclear factor (NF)-kappa-B activation and I-kappa-B-alpha expression in deoxycorticosterone acetate-salt hypertensive rats. (A) The NF-kappa-B binding activity in the left ventricle of deoxycorticosterone acetate-salt rats. Binding specificity was assessed using an ELISA-based format, as described in the Methods. Absorbance was measured at 655 nm. Data are expressed as the mean value ± SEM. *p < 0.05 vs. UN control, p < 0.05 vs. DOCA-V. (B) Representative Western blots of I-kappa-B-alpha protein in the left ventricle of UN control, DOCA-V, and DOCA-F rats. Abbreviations as in Figure 1.