Click on image to view larger version.

Figure 5 Representative current traces of the E-4031-insensitive current, as I_Ks, in rabbits of the control (a) and beta groups (b). The I_Ks elicited by the voltage-clamp protocol in the inset was normalized to the cell capacitance. Measured maximum outward tail currents were averaged and plotted against the test potential (c). The I_Ks density obtained in the beta group rabbits was significantly smaller than that in the control group rabbits. (Data were obtained from isolated left ventricular myocytes from the M-cell region.) C = control.