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Figure 1 Urinary excretion of 11-dehydro thromboxane B₂ (Tx-M) in patients on fradafiban alone, aspirin alone, or aspirin plus nimesulide prior to and at selected intervals during and following percutaneous transluminal coronary angioplasty (PTCA). Urinary Tx-M was higher in the fradafiban group prior to PTCA than in normal subjects (p < 0.05) and increased markedly during the procedure compared with aspirin alone (p < 0.0001).