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Figure 1 Left ventricular developed pressure (LVDP), maximum rate of left ventricular pressure rise (dP/dt_max), and coronary perfusion pressure (CPP) of isolated and perfused heart from rats treated with saline (control), endotoxin (10 mg/kg), endotoxin and N-nitro-L-arginine methyl ester (LNAME) (50 mg/kg), endotoxin and mercaptoethylguanidine (MEG) sodium succinate (10 mg/kg), and endotoxin and 5,10,15,20-tetrakis(4-sulfonatophenyl)-porphyrinato iron (III) (FeTPPS) (30 mg/kg). See Methods section for treatment group design. Results are expressed as mean ± SEM (n = 8 in each group). *p < 0.01 compared with control; #p < 0.01 compared with endotoxin-treated rats.