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Figure 3 Subgroup analysis: percentage of participants developing a depressed left ventricular ejection fraction by baseline quartile of echocardiographic left ventricular mass (LVM) indexed to body surface area (BSA). "No coronary artery disease" subgroup consisted of participants without prevalent or interval myocardial infarction, coronary artery bypass grafting, or percutaneous transluminal angioplasty. "No diabetes" and "no heart failure" excluded participants with these conditions present at baseline, and "no atrial fibrillation" excluded those with atrial fibrillation at baseline or during follow-up. P < 0.001 for the association of LVM/BSA and incident depressed ejection fraction for all groups shown. White bars = quartile 1; bars with horizontal lines = quartile 2; bars with diagonal lines = quartile 3; black bars = quartile 4. Quartile values of echocardiographic LVM/BSA are as reported in Figure 2.