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Figure 1 Brugada syndrome (BrS) population. Among the BrS cohort followed in both institutions, 80 patients were asymptomatic. From 1999, hydroquinidine therapy was prescribed to asymptomatic patients with BrS and inducible arrhythmia (*) (n = 31). In case of noninducibility, patients were not treated, except in case of multiple familial sudden deaths. In case of drug-induced BrS with a normal baseline electrocardiogram (n = 12), the electrophysiologic (EP) study was not performed. The study population also includes four BrS patients () who had multiple implantable cardioverter-defibrillator (ICD) shocks. SD = sudden death; VF = ventricular fibrillation.