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Figure 2 Temporal changes in myocardial contrast intensity (CI) and calibrated CI after bolus injection of Levovist in normal volunteers. Relationships of time points with myocardial CI (left) and calibrated CI (right) at 12 myocardial segments are shown. Data points (circles) indicate the mean values at 12 different segments. Standard deviation (SD) ranged from 1.4 to 2.3 dB. Rectangles and vertical lines at both sides indicate the mean value ± SD among all normal segments. Myocardial CI significantly decreased from 60 to 100 s after injection. Calibrated CI showed no remarkable change, however.