Click on image to view larger version.

Figure 6 Protein content of protein kinase C (PKC)-epsilon. (A) Immunoblotting showed that the PKC-epsilon content in the particulate fraction was increased in noninfarcted viable myocardium of the untreated myocardial infarction (MI) animals (MI/control [C]) as compared with shams. Candesartan treatment of MI animals (MI/angiotensin II type 1 receptor blocker [ARB]) reduced the PKC-epsilon protein level in the particulate fraction, as compared with MI/C. (B) Immunoblotting showed that there was no significant difference in PKC-epsilon content in the supernatant fraction among the three groups. *p < 0.001 MI/C vs. sham; p < 0.001 MI/ARB vs. MI/C; n = 6 in each group.