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Figure 2 Ratios of messenger ribonucleic acid expression ß-myosin heavy chain (MHC) to -MHC and of atrial natriuretic factor (ANF) to glyceraldehyde-3-phosphate-dehydrogenase (GAPDH) in the left ventricle of sham-operated rats (Sham) and in the noninfarcted left ventricular myocardium of rats with extensive myocardial infarction (P MI): Effects of aldosterone receptor inhibition (E), ACE inhibition (T), or combined aldosterone and ACE inhibition (E+T). Mean ± SEM (n = 5 to 7). *p < 0.05 versus Sham; p < 0.05, p < 0.005, p = 0.0001 versus P MI; #p < 0.05 versus E MI.