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Figure 1 Relative risk of death with various creatine kinase-MB isoenzyme (CK-MB) elevations. Each study is shown by the risk ratio estimate and the corresponding 95% confidence interval. Also shown is the summary estimate for all studies. (A) One- to five-fold elevation versus normal CK-MB. (B) Three- to five-fold elevation versus normal CK-MB. (C) Three- to five-fold elevation versus normal CK-MB. (D) >5-fold elevation versus normal CK-MB.