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Figure 3 Serial changes in activated partial thromboplastin time (aPTT) between the two conjunctive treatment groups. The aPTT was significantly prolonged in the heparin group, though not in the activated protein C (APC) group. *p < 0.05 vs. pre in the heparin treatment group. p < 0.01 between the two groups at each sampling point. The center lines in the columns show the median value, and the box plots show the ranges between the 25th and 75th percentile values. The bars attached to the columns show the ranges between the 10th and 90th percentile values. Solid columns = APC group; open columns = heparin group.