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Figure 3 Exercise training (black bars) was effective in reducing local inducible nitric oxide synthase (iNOS) messenger ribonucleic acid (mRNA) expression (A), iNOS protein content (B), and nitrotyrosine (C) after six months. No change was observed in the control group (open bars). **p < 0.01 versus control group at six months; $p < 0.05 versus respective baseline; #p < 0.05; ##p < 0.01 for change at six months from baseline in training versus control group.