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Figure 1 Mean standing systolic and diastolic blood pressure (BP) in tadalafil (20 mg)- and placebo-treated subjects. Sublingual nitroglycerin (0.4 mg) is indicated by the dashed vertical line. The 4- to 96-h time intervals represent time of nitroglycerin administration after the last dose of tadalafil or placebo. In each graph, the upper set of curves represent systolic BP and the lower set of curves represent diastolic BP. Standard deviation for systolic and diastolic BP ranged from 12 to 19 mm Hg and 9 to 13 mm Hg, respectively.