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Figure 3 (A) Representative light microscopic photomicrographs of Masson’s trichrome-stained myocardial sections obtained from control (a), diabetes mellitus (DM) (b), myocardial infarction (MI) (c), and DM+MI (d) mice. Scale bar represents 10 µm. (B) Summarized data for myocyte cross-sectional area from control (n = 8), DM (n = 8), MI (n = 9), and DM+MI (n = 8) mice. (C) Representative light microscopic photomicrographs of sirius red-stained myocardial sections obtained from MI (a) and DM+MI (b) mice. Scale bar represents 10 µm. (D) Summarized data for collagen volume fraction from control (n = 6), DM (n = 6), MI (n = 6), and DM+MI (n = 6) mice. Values are means ± SEM. **p < 0.01 compared with the control value; p < 0.01 compared with the corresponding MI value.