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Figure 2 Comparison of I_K1 in nontransgenic (Ntg) and trangenic (Tg) animals. Averaged peak current density-voltage relation plotted for cells from 2-, 4-, 8-, and 9- to 12-month-old Ntg and Tg mice, respectively (A). Families of representative current traces elicited from a holding potential of –40 mV using voltage steps of 500 ms from –140 mV to +100 mV in 20 mV increments (B) from Ntg (C) as compared with Tg (D) myocyte.