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Figure 7 Lectin-like oxidized low-density lipoprotein receptor (LOX-1) expression and cardiac dysfunction during ischemia-reperfusion (I-R) and dP/dt and mean arterial blood pressure (MABP) during ischemia. Reperfusion further reduced dP/dt, MABP, and heart rate. Administration of LOX-1 antibody significantly improved dP/dt, MABP, and heart rate, whereas nonspecific immunoglobulin G (IgG) had no effect.