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Figure 4 Reduced transient outward potassium current (Ito) in rapid atrial pacing (RAP). (A) A representative set of Ito recordings from a cell of the control group (P0), after 24 h (P24), and after 96 h (P96) of RAP. (B) IV relation of Ito current densities. TP = test potential. *p < 0.05, **p < 0.01, ***p < 0.001 vs. P0 (One-way analysis of variance. Comparisons between multiple groups were performed with a Bonferroni corrected t test).