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Figure 4 A clinical efficacy summary: low-molecular-weight heparin (LMWH) vs. unfractionated heparin (UFH). ESSENCE = Efficacy and Safety of Subcutaneous Enoxaparin in Non–Q-wave Coronary Events trial; FRAXIS = FRAXiparine in Ischemic Syndromes trial; FRIC = FRagmin In unstable Coronary artery disease trial; MI = myocardial infarction; NS = not significant; RRR = relative risk reduction; TIMI = Thrombolysis In Myocardial Infarction. (Adapted [with permission from Thieme Publishers, 2002] from Semin Thromb Hemost 1999;25 Suppl 3:113–21 [Figure 3]).