Click on image to view larger version.

Figure 1 Results of the multipoint linkage analysis for the 10 primary pulmonary hypertension families on chromosome 2q31-q33. The thin line (Z) indicates the cumulative lod scores assuming homogeneity. The thick line indicates the maximum lod score when allowing for heterogeneity (Z_(het)max). Indicated above the x-axis are the map positions of the markers. Also indicated is the map position of the bone morphogenetic protein receptor type 2 gene (BMPR2) locus.